
trans-Urocanic Acid
CAS No. 3465-72-3
trans-Urocanic Acid( —— )
Catalog No. M34957 CAS No. 3465-72-3
trans-Urocanic Acid ((E)-Urocanic acid), a compound predominantly distributed in the hippocampus and prefrontal cortex, is an isomer of cis-UCA, an epidermal UV-protectant, which enhances the stability of tenofovir eplerenomide in long-acting HIV applications.
Purity : >98% (HPLC)






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Biological Information
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Product Nametrans-Urocanic Acid
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NoteResearch use only, not for human use.
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Brief Descriptiontrans-Urocanic Acid ((E)-Urocanic acid), a compound predominantly distributed in the hippocampus and prefrontal cortex, is an isomer of cis-UCA, an epidermal UV-protectant, which enhances the stability of tenofovir eplerenomide in long-acting HIV applications.
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Descriptiontrans-urocanic acid (trans-UCA), a natural epidermal constituent, inhibits human natural killer cell (NK) activity in vitro. trans-urocanic acid is active in regulating an immune function.
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In Vitrotrans-urocanic acid (trans-UCA) partially inhibits cytotoxic function of IL-2-activated NK cells and reduces IL-2-induced activation of NK cells. trans-urocanic acid (trans-UCA;100 μg/mL) slightly decreases cell proliferation and viability of primary human keratinocytes.Cell Proliferation Assay Cell Line:Primary human keratinocytes Concentration:100 μg/mL Incubation Time:24 hours Result:Decreased cell proliferation and viability.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number3465-72-3
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Formula Weight138.12
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Molecular FormulaC6H6N2O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (724.01 mM; Ultrasonic )
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SMILESC(=C/C(O)=O)\C1=CN=CN1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. J Uksila, et al. Trans-urocanic acid, a natural epidermal constituent, inhibits human natural killer cell activity in vitro. Exp Dermatol. 1994 Apr;3(2):61-5.?
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